Which of the following is considered a potential complication of Cushing's Syndrome?

Weakness of the bones is indeed a significant potential complication of Cushing's Syndrome, which arises primarily from prolonged exposure to high levels of cortisol. In this condition, the overproduction of cortisol can lead to a decrease in bone density, making the bones fragile and more susceptible to fractures. This occurs as cortisol interferes with the bone-remodeling process, leading to decreased formation of new bone and increased resorption of existing bone.

In addition, other factors associated with Cushing's Syndrome, such as weight gain and the redistribution of fat, can further contribute to complications related to mobility and overall physical health. Recognizing bone weakness as a complication underscores the importance of monitoring bone health and implementing measures to prevent fractures in individuals with Cushing's Syndrome.