Which neurotransmitter is primarily targeted by MAOIs?

Monamine oxidase inhibitors (MAOIs) primarily target the neurotransmitters norepinephrine, serotonin, and dopamine. These medications work by inhibiting the enzyme monoamine oxidase, which is responsible for breaking down these neurotransmitters in the brain. As a result, MAOIs effectively increase the levels of these neurotransmitters, leading to enhanced mood and relief from symptoms of depression.

By blocking the breakdown of these three neurotransmitters, MAOIs can significantly improve mood and overall emotional regulation. This broad action on multiple neurotransmitters is why the answer indicates that all of the options are correct. The inclusion of all three neurotransmitters demonstrates the comprehensive mechanism of action that MAOIs have in the treatment of mood disorders.