What symptom is associated with Guillain-Barré syndrome?

The symptom associated with Guillain-Barré syndrome is ascending paralysis. This syndrome is characterized by the rapid onset of muscle weakness and paralysis that typically starts from the lower extremities and ascends toward the upper body and respiratory muscles. Patients often first notice weakness in their legs that can progress to involve the arms and, in severe cases, can lead to respiratory failure if the muscles that control breathing become affected.

Ascending paralysis in Guillain-Barré syndrome is a hallmark feature, and the condition often follows a viral infection, where the immune system mistakenly attacks the peripheral nerves, leading to inflammation and impairment of nerve function. The progressive nature of this paralysis is significant because it helps differentiate Guillain-Barré from other conditions that may present with weakness or paralysis.