What is the primary characteristic of Addison's Disease?

Addison's Disease is primarily characterized by the under secretion of adrenal hormones, particularly cortisol and aldosterone, due to damage or dysfunction of the adrenal glands. This condition leads to various physiological changes, including increased sensitivity to stress, imbalances in electrolytes, and disruptions in metabolism. The adrenal glands, which are responsible for producing essential hormones that help regulate metabolism, immune response, and blood pressure, do not produce sufficient amounts of these hormones in individuals with Addison's Disease.

As a result of this underproduction, patients might experience symptoms such as fatigue, muscle weakness, weight loss, and low blood pressure. The inadequate secretion of these hormones impacts the body's ability to respond effectively to stress, resulting in an inability to maintain homeostasis under physical or psychological stressors. This underscores the importance of recognizing the primary characteristic of Addison's Disease as it relates to adrenal hormone secretion levels.