What digoxin level is considered toxic?

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Digoxin toxicity is generally considered when serum levels exceed 2.0 ng/mL. At this concentration, the risk of experiencing adverse effects, such as gastrointestinal disturbances, neurological symptoms, and heightened cardiac arrhythmias, significantly increases. Because digoxin has a narrow therapeutic range, levels should be regularly monitored in patients receiving the medication.

While lower levels, such as anything over 1.5 ng/mL, may prompt caution, toxicity is more definitively linked to levels above 2.0 ng/mL. Other levels mentioned in the choices reflect degrees of toxicity that can lead to severe complications; however, the consensus in clinical guidelines and literature places a stronger emphasis on the critical threshold of 2.0 ng/mL as indicative of toxicity.

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