What are the common side effects of Tricyclic antidepressants, represented by the acronym ABCDE?

Tricyclic antidepressants (TCAs) are known for their anticholinergic effects, which is accurately represented by the acronym ABCDE. Anticholinergic side effects occur because these medications block the action of acetylcholine, a neurotransmitter that plays a key role in various bodily functions, including the regulation of the autonomic nervous system.

Common anticholinergic effects include dry mouth, constipation, urinary retention, blurred vision, and confusion. These side effects are particularly prevalent in older adults, who may be more sensitive to them. Knowing about the anticholinergic effects is critical for nursing practice as it informs monitoring for potential complications and educating patients about what to expect when taking these medications.

While other options might seem related to medication effects, they are not characteristic of TCAs. This reinforces the importance of understanding the specific pharmacological effects of different classes of medications.